QLG funded projects

Building planes and teaching how to fly them; or, not only developing questionnaires.

Members of the QLG are also engaged in a number of clinical and methodological projects, all aiming, in one way or another, to provide the means to ensure that patients’ voices are heard loud and clear in clinical and translational research on a daily basis.

This page will give you an overview of the many different activities.

Support for QLQ-C30 and Modules

Minimal Important Difference (MID)

Evaluating content validity of the EORTC QLQ-C30

Development of response criteria for longitudinal health-related quality of life data in oncology clinical trials (Q-RECIST)

Development of thresholds for the EORTC QLQ-C30 and the EORTC CAT measures to enable their use for symptom screening in daily clinical practice

Development of an online platform to support module development and dissemination of the EORTC CAT measures (CHES platform)

Development of EORTC/CLTF questionnaires to assess HRQOL in primary cutaneous T-cell and B-cell lymphomas: Phase I-II.

Investigating and improving the German response scales of the EORTC core questionnaire for assessing the quality of life in cancer patients (EORTC QLQ-C30) – a three-step approach

Development and evaluation of an e-learning programme on EORTC Quality of life measures in clinical practice) QOL_E-Learning

Development of an interpretation guideline for the EORTC PRO measures

Update of the EORTC QLQ reference values manual (RefVal)

Prospective Minimal Important Difference (pMID) Project: Interpreting changes in EORTC QLQ-C30 scores by anchoring to patients’ rating of change - Phase I

Improving compliance and standard of data collection and use in trials: setting standards for the next generation

Support for CAT

Development and validation of the EORTC computerized adaptive testing (CAT) instrument

Comparative evaluation of the computer-adaptive EORTC quality of life measures

Collection of Normative Data for the EORTC CAT

Development of thresholds for the EORTC QLQ-C30 and the EORTC CAT measures to enable their use for symptom screening in daily clinical practice

Development of an online platform to support module development and dissemination of the EORTC CAT measures (CHES platform)

Evaluating the use of the EORTC PRO measures for improving inter-rater reliability of CTCAE ratings

Support for the Utility measures

Determination of European Utility Weights for a Cancer-Specific Preference-Based Quality of Life Measure Derived From the EORTC QLQ-C30

Comparison of the EORTC QLU-C10D with generic utility instruments and development of a comprehensive manual for its use

Establishing thresholds for clinical importance for disease-specific EORTC questionnaire modules

Development of an interpretation guideline for the EORTC PRO measures

Long-term follow-up / Survivors

Follow-up in Early and Locally Advanced Breast Cancer Patients: An EORTC QLG-BCG-ROG Protocol

Routine Follow-up of Gynecological Cancer Patients: A joint EORTC QLG-GCG protocol

Assessment of the Quality of Life of childhood acute lymphoblastic leukemia patients enrolled in EORTC Children Leukemia Group trials between 1971 and 1998

Late Toxicity and Long-term Quality of Life in Head and Neck Cancer Survivors

Long-term Quality of Life in Acute Myeloid Leukemia Survivors Treated in Randomized Controlled Trials and in Real-Life Settings

Understanding the long-term implications of treatment of rare brain tumours on health-related quality of life: A European cross-sectional study

Long-term survivorship challenges of advanced/metastatic GIST patients responding to Imatinib treatment: An observational study

Reviews / Meta-analyses

Type and DIREction of Clinical and patient-reported outcomes in cancer Trials RepositORY Project (DIRECTORY)

Predictors of quality of life ratings from patients with primary brain tumors: the role of self-awareness and cognitive functioning

Combining clinical trial datasets in glioma patients: the added value of health-related QOL assessment (CODAGLIO)

Cancer Clinical Trials Pooling of Quality Life Data (CATAPULT) initiative