In this international phase IV field study, we evaluated the psychometric characteristics of the EORTC QLQ-TC26 module in an sample of 313 testicular cancer patients. In line with the EORTC Module Development Guidelines, these patients were from Southern, Western, Northern and Eastern Europe. The final QLQ-TC26 comprises seven multi-item scales (treatment side effects, treatment satisfaction, future perspective, communication, sexual activity, functioning and enjoyment) and six single items (job and education problems, physical limitations, family problems, infertility, body image problems, testicular transplant satisfaction).
The hypothesised scale structure of the QLQ-TC26 was supported by confirmatory factor analysis and satisfactory internal consistency.
The EORTC QLQ-TC26 is a valid, reliable and well-accepted condition-specific questionnaire, supplementing the EORTC QLQ-C30, for the assessment of testicular cancer patients’ HRQOL in clinical trials.