Lung Cancer (update of QLQ-LC13)

Gender Neutral
Type Module
Testing Phase IV - in development
Principal investigator(s)
Michael Koller
Regensburg, Germany

Project summary

The update of the EORTC questionnaire for assessing quality of life in lung cancer follows a rigorous methodology including patient involvement on various levels. The updated questionnaire after Phases 1 to 3 comprises, in addition to the original items, new items related to the side-effects of targeted therapies and surgery. The updated module currently undergoes full validation and psychometric testing in a cross-cultural, multicenter Phase 4 study, involving 17 centers from 11 different countries. The updated module should become the new standard for quality of life assessment in lung cancer clinical trials.

Achievements

Phase 1 to 3 of the standard module development process have been completed.

Future plans

Data entry, query management, cleaning the data, psychometric analyses, project report by the end of 2018.

For patients

Quality of life is a major concern for lung cancer patients. Two decades ago the EORTC has developed a lung cancer module to assess patients’ quality of life. The goal of the current project is to update this module in order to catch up with new developments in the diagnosis and treatment for patients with lung cancer.

Publications

Koller M, Hjermstad MJ,Tomaszewski KA, Tomaszewska IM, Hornslien K, Harle A, Arraras JI, Morag O, Pompili C, Ioannidis G, Georgiou M, Navarra C, Chie WC, Johnson CD, Himpel A, Schulz C, Bohrer T, Janssens A, Kuliś D, Bottomley A on behalf of the EORTC Quality of Life Group, EORTC Lung Cancer Group, and European Society of Thoracic Surgeons. An international study to revise the EORTC questionnaire for assessing quality of life in lung cancer patients Ann Oncol. 2017 Nov 1;28(11):2874-2881. doi: 10.1093/annonc/mdx453.

Koller M, Hjermstad MJ, Tomaszewski KA, Harle A, Arraras JI, Morag O, Pompili C, Ioannidis G, Navarra C, Chie WC, Johnson C, Himpel A, Schulz C, Hofmann HS, Müller K, Kulis D, Bottomley A. Update of the EORTC module for assessing quality of life in patients with lung cancer – introducing the EORTC QLQ-LC29. 16. Deutscher Kongress für Versorgungsforschung (DKVF). Berlin, 04.-06.10.2017. Düsseldorf: German Medical Science GMS Publishing House; 2017. DOI: 10.3205/17dkvf022