Childhood acute lymphoblastic leukemia

This project focused on analyzing and interpreting Quality of Life (QOL) data collected between 2012 and 2017 during the EORTC CLG 58LAE (Late Adverse Effects) project. The original project investigated long-term outcomes in childhood acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) survivors (≥18 years) who had been enrolled as children (<18 years) in the EORTC CLG treatment protocols 58741 (1971–1978), 58831/2 (1983–1989), and 58881 (1989–1998).

During this project, we reported on QOL data from three questionnaires completed by survivors: The SF12, The Impact of Cancer for Childhood Cancer Survivors (IOC-CS), and the Quality of Life Systemic Inventory (QLSI).

We worked on three manuscripts linked to this project:
1) Quality of life of long-term childhood acute lymphoblastic leukemia survivors enrolled between 1971 and 1998 in EORTC CLG studies compared to healthy controls: results of the 58LAE study;
2) Sociodemographic and medical determinants of long-term quality of life in acute lymphoblastic leukemia survivors an EORTC investigation;
3) The use of Health Status and Quality of Life measures in long-term childhood acute lymphoblastic leukemia survivors enrolled in EORTC CLG studies: a methodological perspective.

All three papers that were planned are published.

The study is completed.

This project examined the Quality of Life (QOL) of a group of survivors of childhood cancer (acute lymphoblastic leukemia). The data was collected between 2012 and 2017. It focused on the long-term impacts of childhood cancer on QOL compared to healthy individuals. It also explored whether there were medical or social influences on QOL. Finally, it assessed the questionnaires used to measure QOL and their usefulness in capturing the experiences of survivors.